CR-4056

CR-4056
Identifiers
	IUPAC name 6-(1H-imidazol-1-yl)-2-phenylquinazoline;
CAS Number	1004997-71-0 ;
PubChem CID	24898732;
ChemSpider	28669340;
UNII	W9SQ1X2NPZ;
Chemical and physical data
Formula	C17H12N4
Molar mass	272.311 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1(C2=CC=CC=C2)=NC=C3C=C(N4C=CN=C4)C=CC3=N1;
	InChI InChI=1S/C17H12N4/c1-2-4-13(5-3-1)17-19-11-14-10-15(6-7-16(14)20-17)21-9-8-18-12-21/h1-12H; Key:CSZGXYBGYFNSCO-UHFFFAOYSA-N;

CR-4056 is an analgesic drug candidate with a novel mechanism of action, acting as a ligand for the imidazoline receptor I₂. It showed promising results in animal studies against various types of neuropathic pain, and has reached Phase II human clinical trials as a potential treatment for pain associated with osteoarthritis.^[1]^[2]^[3]^[4]^[5]

Quick facts Identifiers, CAS Number ...

Close

See also

Identifiers

IUPAC name 6-(1H-imidazol-1-yl)-2-phenylquinazoline
CAS Number	1004997-71-0^Y
PubChem CID	24898732
ChemSpider	28669340
UNII	W9SQ1X2NPZ
Chemical and physical data
Formula	C₁₇H₁₂N₄
Molar mass	272.311 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1(C2=CC=CC=C2)=NC=C3C=C(N4C=CN=C4)C=CC3=N1
InChI InChI=1S/C17H12N4/c1-2-4-13(5-3-1)17-19-11-14-10-15(6-7-16(14)20-17)21-9-8-18-12-21/h1-12H Key:CSZGXYBGYFNSCO-UHFFFAOYSA-N