CREB3L1

CREB3L1
Identifiers
Aliases	CREB3L1, OASIS, cAMP responsive element binding protein 3-like 1, cAMP responsive element binding protein 3 like 1, OI16
External IDs	OMIM: 616215; MGI: 1347062; HomoloGene: 8058; GeneCards: CREB3L1; OMA:CREB3L1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	46,321,409 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	91,854,847 bp
RNA expression pattern
	Top expressed in
	nasal epithelium; ; stromal cell of endometrium; ; mucosa of ileum; ; myocardium of left ventricle; ; body of pancreas; ; mucosa of paranasal sinus; ; pylorus; ; right ventricle; ; apex of heart; ; rectum;
	Top expressed in
	calvaria; ; parotid gland; ; molar; ; submandibular gland; ; membranous bone; ; left colon; ; choroid plexus of fourth ventricle; ; yolk sac; ; long bone; ; Dermatocranium;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; chromatin binding; protein binding; cAMP response element binding; SMAD binding; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; endoplasmic reticulum; nucleus; membrane;
Biological process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; regulation of transcription, DNA-templated; extracellular matrix constituent secretion; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress; transcription, DNA-templated; multicellular organism development; endoplasmic reticulum unfolded protein response; response to unfolded protein; osteoblast differentiation; positive regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; positive regulation of collagen biosynthetic process; negative regulation of transcription by RNA polymerase II; negative regulation of gene expression; negative regulation of fibroblast growth factor receptor signaling pathway; negative regulation of transcription, DNA-templated; negative regulation of sprouting angiogenesis;
	Sources:Amigo / QuickGO
Orthologs
	90993
	26427
	ENSG00000157613
	ENSMUSG00000027230
	Q96BA8
	Q9Z125
	NM_052854
	NM_011957
	NP_443086
	NP_036087
	Wikidata
View/Edit Human	View/Edit Mouse

CAMP responsive element binding protein 3 like 1, also known as OASIS, is a responsive element binding protein that in humans is encoded by the CREB3L1 gene.^[5]