CSRP1

Cysteine and glycine-rich protein 1 is a protein that in humans is encoded by the CSRP1 gene.^[5][6][7]

AliasesCSRP1, CRP, CRP1, CSRP, CYRP, D1S181E, HEL-141, HEL-S-286, cysteine and glycine rich protein 1

External IDsOMIM: 123876; MGI: 88549; HomoloGene: 37874; GeneCards: CSRP1; OMA:CSRP1 - orthologs

Chr.Chromosome 1 (human)^[1]

End201,509,456 bp^[1]

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CSRP1
Identifiers
Aliases	CSRP1, CRP, CRP1, CSRP, CYRP, D1S181E, HEL-141, HEL-S-286, cysteine and glycine rich protein 1
External IDs	OMIM: 123876; MGI: 88549; HomoloGene: 37874; GeneCards: CSRP1; OMA:CSRP1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q32.1 Start 201,483,530 bp[1] End 201,509,456 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 E4 Start 135,647,799 bp[2] End 135,679,970 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in popliteal artery tibial arteries right coronary artery muscle layer of sigmoid colon saphenous vein body of uterus left uterine tube gastric mucosa tail of epididymis smooth muscle tissue Top expressed in ascending aorta aortic valve tunica media of zone of aorta seminal vesicula uterus deep cerebellar nuclei globus pallidus umbilical cord pyloric antrum lateral geniculate nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function metal ion binding RNA binding zinc ion binding Cellular component extracellular exosome focal adhesion nucleus Biological process platelet aggregation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1465 13007 Ensembl ENSG00000159176 ENSMUSG00000026421 UniProt P21291 P97315 RefSeq (mRNA) NM_004078 NM_001144773 NM_001193570 NM_001193571 NM_001193572 NM_007791 NM_001360782 RefSeq (protein) NP_001180499 NP_001180500 NP_001180501 NP_004069 NP_031817 NP_001347711 Location (UCSC) Chr 1: 201.48 – 201.51 Mb Chr 1: 135.65 – 135.68 Mb PubMed search [3] [4]
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CSRP1 is a member of the CSRP family of genes encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in CRP1 is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation Other genes in the family include CSRP2 and CSRP3.^[7]