CTNNBIP1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Beta-catenin-interacting protein 1 is a protein that is encoded in humans by the CTNNBIP1 gene.[5][6]

PDBOrtholog search: PDBe RCSB
AliasesCTNNBIP1, ICAT, catenin beta interacting protein 1
Quick facts Available structures, PDB ...
CTNNBIP1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCTNNBIP1, ICAT, catenin beta interacting protein 1
External IDsOMIM: 607758; MGI: 1915756; HomoloGene: 10641; GeneCards: CTNNBIP1; OMA:CTNNBIP1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020248
NM_001012329

NM_001141930
NM_023465

RefSeq (protein)

NP_001012329
NP_064633

NP_001135402
NP_075954

Location (UCSC)Chr 1: 9.85 – 9.91 MbChr 4: 149.6 – 149.65 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF (T-cell transcription factor) family members. The encoded protein is a negative regulator of the Wnt signaling pathway.[5]

References

Further reading

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