Wikiwand AI

Cathepsin O

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Cathepsin O is an enzyme encoded by the CTSO gene in humans.[5][6]

AliasesCTSO, CTSO1, cathepsin O
External IDsOMIM: 600550; MGI: 2139628; GeneCards: CTSO
PDBOrtholog search: PDBe RCSB
Quick facts CTSO, Identifiers ...
CTSO
Identifiers
AliasesCTSO, CTSO1, cathepsin O
External IDsOMIM: 600550; MGI: 2139628; GeneCards: CTSO
Available structures
PDBOrtholog search: PDBe RCSB
Enzyme activity
EC #BRENDAExPASyKEGGMetaCyc
3.4.22.42↗↗↗↗
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001334

NM_177662

RefSeq (protein)

NP_001325

NP_808330

Location (UCSC)Chr 4: 155.92 – 155.95 MbChr 3: 81.84 – 81.86 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

Cathepsin O is a cysteine cathepsin, a cysteine protease and a member of the cathepsin family. This proteolytic enzyme is involved in cellular protein degradation and turnover. The recombinant form of this enzyme was shown to degrade synthetic peptides typically used as substrates for cysteine proteinases, and its proteolytic activity was abolished by an inhibitor of cysteine proteinase.[6]

References

Further reading

Related Articles

Timelines

Top Qs

Fact Checks