CYFIP1

CYFIP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3P8C, 4N78
Identifiers
Aliases	CYFIP1, P140SRA-1, SHYC, SRA-1, SRA1, cytoplasmic FMR1 interacting protein 1
External IDs	OMIM: 606322; MGI: 1338801; HomoloGene: 22628; GeneCards: CYFIP1; OMA:CYFIP1 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	22,981,063 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	55,582,350 bp
RNA expression pattern
	Top expressed in
	germinal epithelium; ; gingival epithelium; ; parietal pleura; ; visceral pleura; ; oral cavity; ; tibia; ; palpebral conjunctiva; ; skin of hip; ; mucosa of sigmoid colon; ; skin of thigh;
	Top expressed in
	saccule; ; otic placode; ; sciatic nerve; ; otic vesicle; ; Ileal epithelium; ; dermis; ; stroma of bone marrow; ; endothelial cell of lymphatic vessel; ; skin of external ear; ; gastrula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	actin binding; protein-containing complex binding; actin filament binding; protein binding; RNA 7-methylguanosine cap binding; translation regulator activity;
Cellular component	extracellular exosome; cytoplasm; synapse; cell projection; cell junction; cytosol; SCAR complex; focal adhesion; lamellipodium; perinuclear region of cytoplasm; ruffle; mRNA cap binding complex; neuron projection; extracellular region; filopodium tip; secretory granule lumen; specific granule lumen; soma; terminal bouton; dendritic spine; dendritic growth cone; axonal growth cone; excitatory synapse; central region of growth cone; peripheral region of growth cone; tertiary granule lumen; postsynapse;
Biological process	Rac protein signal transduction; cognition; Fc-gamma receptor signaling pathway involved in phagocytosis; multicellular organism development; ruffle organization; axon extension; vascular endothelial growth factor receptor signaling pathway; nervous system development; regulation of cell shape; cell differentiation; positive regulation of Arp2/3 complex-mediated actin nucleation; lamellipodium assembly; cellular response to insulin stimulus; neutrophil degranulation; positive regulation of axon extension; positive regulation of axonogenesis; response to electrical stimulus; positive regulation of dendrite development; positive regulation of ruffle assembly; negative regulation of synaptic vesicle recycling; neuron projection development; positive regulation of neurotrophin TRK receptor signaling pathway; dendrite extension; regulation of translation; modification of synaptic structure; cell morphogenesis; axon guidance; cell projection assembly; regulation of translation at postsynapse, modulating synaptic transmission; regulation of modification of postsynaptic actin cytoskeleton;
	Sources:Amigo / QuickGO
Orthologs
	23191
	20430
	ENSG00000280618; ENSG00000273749; ENSG00000288461
	ENSMUSG00000030447
	Q7L576
	Q7TMB8
NM_001033028; NM_001287810; NM_014608; NM_001324119; NM_001324120;
	NM_001324122; NM_001324123; NM_001324124; NM_001324125; NM_001324126
	NM_001164661; NM_001164662; NM_011370
NP_001028200; NP_001274739; NP_001311048; NP_001311049; NP_001311051;
	NP_001311052; NP_001311053; NP_001311054; NP_001311055; NP_055423
	NP_001158133; NP_001158134; NP_035500
	Wikidata
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