Caffeine synthase
Enzyme
From Wikipedia, the free encyclopedia
Caffeine synthase is a methyltransferase enzyme involved in the caffeine biosynthesis pathway. It is expressed in tea species, coffee species, and cocoa species. The enzyme catalyses the following reactions:[1]
- S-adenosyl-L-methionine + theobromine S-adenosyl-L-homocysteine + caffeine + H+
- S-adenosyl-L-methionine + paraxanthine S-adenosyl-L-homocysteine + caffeine + H+
- 7-methylxanthine + S-adenosyl-L-methionine S-adenosyl-L-homocysteine + H+ + theobromine
| Caffeine synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.160 | ||||||||
| CAS no. | 155215-94-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Caffeine synthase is expressed in the Camellia species irrawadiensis, ptilophylla, and sinensis;[2] the Coffea species arabica,[3][4] and canephora;[5] and in Theobroma cacao.[6]
