Calfactant

Mixture used in medicine From Wikipedia, the free encyclopedia

Calfactant, also known as Infasurf,[1] is an intratracheal suspension derived from the natural surfactant in calf lungs. It is used in premature infants with lung surfactant deficiency that causes infant respiratory distress syndrome (IRDS).[2]

Trade namesInfasurf
Pregnancy
category
  • N
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Calfactant
Clinical data
Trade namesInfasurf
Pregnancy
category
  • N
ATC code
  • none
Legal status
Legal status
Identifiers
CAS Number
ChemSpider
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UNII
ChEMBL
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Mechanism of action

Lung surfactant is essential for effective ventilation as it modifies alveolar surface tension.[3] IRDS is caused by a lung surfactant deficiency. Calfactant serves as a substitute for the natural surfactant.[2]

References

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