Calphostin
Class of fungi
From Wikipedia, the free encyclopedia
The calphostins are a class of closely related chemical compounds isolated from the fungus Cladosporium cladosporioides.[1][2] The known calphostins include calphostin A, calphostin B, calphostin C, calphostin D, and calphostin I. The calphostins are inhibitors of protein kinase C (PKC).[1][2] The most potent member of the series, calphostin C,[1] has found use as a biochemical tool because of this activity.[3]
 | ||
| Calpohostin | R1 | R2 |
| Calphostin A | Bz | Bz |
| Calphostin B | Bz | H |
| Calphostin C | Bz | 4-(HO)Bz |
| Calphostin D | H | H |
| Calphostin I | 4-(HO)Bz | 4-(HO)Bz |
Calphostin C
Calphostin C is a potent inhibitor of protein kinase C (PKC).[1][2][3]
