CatSper3

CATSPER3
Identifiers
Aliases	CATSPER3, CACRC, CatSper3, cation channel sperm associated 3
External IDs	OMIM: 609120; MGI: 1924106; HomoloGene: 12658; GeneCards: CATSPER3; OMA:CATSPER3 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	135,011,696 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	55,956,811 bp
RNA expression pattern
	Top expressed in
	sperm; ; right testis; ; left testis; ; testicle; ; gonad; ; gastrocnemius muscle; ; muscle of thigh; ; right uterine tube; ; mucosa of transverse colon; ; gastric mucosa;
	Top expressed in
	spermatid; ; seminiferous tubule; ; embryo; ; spermatocyte; ; embryo; ; primary oocyte; ; muscle of thigh; ; zygote; ; proximal tubule; ; digastric muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	voltage-gated calcium channel activity; calcium channel activity; voltage-gated ion channel activity; ion channel activity; cation channel activity;
Cellular component	integral component of membrane; CatSper complex; cell projection; membrane; plasma membrane; cilium; acrosomal vesicle; endoplasmic reticulum; motile cilium;
Biological process	flagellated sperm motility; cell differentiation; membrane depolarization during action potential; sodium ion transport; regulation of ion transmembrane transport; ion transport; multicellular organism development; ion transmembrane transport; calcium ion transmembrane transport; transmembrane transport; spermatogenesis; sperm-egg recognition; sperm capacitation; calcium ion transport; response to progesterone;
	Sources:Amigo / QuickGO
Orthologs
	347732
	76856
	ENSG00000152705
	ENSMUSG00000021499
	Q86XQ3
	Q80W99
	NM_178019
	NM_001252487; NM_001252488; NM_029772
	NP_821138
	NP_001239416; NP_001239417; NP_084048
	Wikidata
View/Edit Human	View/Edit Mouse

CatSper3, is a protein which in humans is encoded by the CATSPER3 gene.^[5]^[6]^[7]^[8] CatSper3 is a member of the cation channels of sperm family of proteins. The four proteins in this family together form a Ca²⁺-permeant ion channel specific essential for the correct function of sperm cells.^[9]