Cefmatilen

Cefmatilen
Clinical data
Routes of; administration	Oral
ATC code	none;
Identifiers
	IUPAC name (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)- 2-(hydroxyimino)acetyl]amino}-8-oxo-3-{[(1H-1,2,3- triazol-4-ylsulfanyl)methyl]sulfanyl}-5-thia-1- azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;
CAS Number	140128-74-1 ; 154776-45-1 (HCl · H2O);
PubChem CID	9690121;
ChemSpider	4912110 ;
UNII	T750UM24H8;
ChEMBL	ChEMBL2104438;
CompTox Dashboard (EPA)	DTXSID50161236 ;
Chemical and physical data
Formula	C15H14N8O5S4
Molar mass	514.57 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)/C(=N\O)/C3=CSC(=N3)N)C(=O)O)SCSC4=NNN=C4;
	InChI InChI=1S/C15H14N8O5S4/c16-15-18-5(2-30-15)8(21-28)11(24)19-9-12(25)23-10(14(26)27)6(3-29-13(9)23)31-4-32-7-1-17-22-20-7/h1-2,9,13,28H,3-4H2,(H2,16,18)(H,19,24)(H,26,27)(H,17,20,22)/b21-8-/t9-,13-/m1/s1 ; Key:UEQVTKSAEXANEZ-YCRCPZNHSA-N ;
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Cefmatilen (INN, codenamed S-1090) is an orally-active cephalosporin antibiotic. It was developed in Japan and first described in 1992.^[1]

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In vitro, cefmatilen is highly active against a variety of Gram-positive and Gram-negative bacteria, including Streptococcus pyogenes and Neisseria gonorrhoeae.^[1]

References

Clinical data

Routes of administration	Oral
ATC code	none
Identifiers
IUPAC name (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)- 2-(hydroxyimino)acetyl]amino}-8-oxo-3-{[(1H-1,2,3- triazol-4-ylsulfanyl)methyl]sulfanyl}-5-thia-1- azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS Number	140128-74-1^Y 154776-45-1 (HCl · H₂O)
PubChem CID	9690121
ChemSpider	4912110^Y
UNII	T750UM24H8
ChEMBL	ChEMBL2104438
CompTox Dashboard (EPA)	DTXSID50161236
Chemical and physical data
Formula	C₁₅H₁₄N₈O₅S₄
Molar mass	514.57 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)/C(=N\O)/C3=CSC(=N3)N)C(=O)O)SCSC4=NNN=C4
InChI InChI=1S/C15H14N8O5S4/c16-15-18-5(2-30-15)8(21-28)11(24)19-9-12(25)23-10(14(26)27)6(3-29-13(9)23)31-4-32-7-1-17-22-20-7/h1-2,9,13,28H,3-4H2,(H2,16,18)(H,19,24)(H,26,27)(H,17,20,22)/b21-8-/t9-,13-/m1/s1^Y Key:UEQVTKSAEXANEZ-YCRCPZNHSA-N^Y
(verify)