Chlorite dismutase
Enzyme
From Wikipedia, the free encyclopedia
Chlorite dismutase, also known as Chlorite O2-lyase (EC 1.13.11.49), is an enzyme that catalyzes the chemical reaction
- ClO−2 → Cl− + O2
| chlorite dismutase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.13.11.49 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Reactions that generate oxygen molecules are exceedingly rare in biology, except in photosynthesis, and they are difficult to mimic synthetically. Perchlorate-respiring bacteria enzymatically detoxify chlorite (ClO−2), the end product of the perchlorate (ClO−4) respiratory pathway, by converting it to dioxygen (O2) and chloride (Cl−).[1] Chlorite dismutase is a hemoprotein, but it bears no structural or sequence relationships with known peroxidases or other heme proteins, and is part of a large family of proteins with more than one biochemical function.
