Chlorphenesin carbamate
Muscle relaxant drug
From Wikipedia, the free encyclopedia
Chlorphenesin carbamate (Maolate, Musil) is a centrally acting muscle relaxant used to treat muscle pain and spasms.[1][2] Chlorphenesin carbamate is no longer used for this purpose in most developed nations due to the availability of much safer spasmolytics such as benzodiazepines.
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| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
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| Excretion | urine |
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| ECHA InfoCard | 100.002.902 |
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| Formula | C10H12ClNO4 |
| Molar mass | 245.66 g·mol−1 |
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| Melting point | 86 to 92 °C (187 to 198 °F) |
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Other central effects include sedation, anxiolysis, and dizziness.
Chlorphenesin
A related chemical, chlorphenesin (C9H11ClO3) without the carbamate group, is used as a preservative in products such as cosmetics. It has antifungal and some antibacterial properties, and is classified as an antifungal for topical use by the WHO.[3]
The major adverse effect from this preservative on skin is allergic contact sensitivity.[4][5] Systemic intoxication from transdermal use has not been observed, although the FDA discourages its use as an ingredient in nipple cream for nursing mothers.[6]