Clogestone acetate

Clogestone acetate
Clinical data
Other names	Chlormadinol acetate; AY-11440; 3β,17α-Diacetoxy-6-chloropregna-4,6-diene-20-one
Drug class	Progestogen; Progestogen ester
Identifiers
	IUPAC name (1S,2R,5S,10R,11S,14R,15S)-14-acetyl-5-(acetyloxy)-8-chloro-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-6,8-dien-14-yl acetate;
CAS Number	3044-32-4;
PubChem CID	20055455;
ChemSpider	16736894;
UNII	6RU186S3NO;
KEGG	D03549;
ChEMBL	ChEMBL2106484;
CompTox Dashboard (EPA)	DTXSID70184523 ;
Chemical and physical data
Formula	C25H33ClO5
Molar mass	448.98 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(=O)C1(CCC2C1(CCC3C2C=C(C4=CC(CCC34C)OC(=O)C)Cl)C)OC(=O)C;
	InChI InChI=1S/C25H33ClO5/c1-14(27)25(31-16(3)29)11-8-20-18-13-22(26)21-12-17(30-15(2)28)6-9-23(21,4)19(18)7-10-24(20,25)5/h12-13,17-20H,6-11H2,1-5H3/t17-,18+,19-,20-,23+,24-,25-/m0/s1; Key:KSCZWFXQKITHSL-OKCNGXCSSA-N;

Clogestone acetate (USANTooltip United States Adopted Name) (developmental code name AY-11440), also known as chlormadinol acetate or as 3β,17α-diacetoxy-6-chloropregna-4,6-diene-20-one,^[1] is a steroidal progestin which was investigated as a progestin-only contraceptive and postcoital contraceptive but was never marketed.^[2]^[3]^[4]^[5] It is the diacetate ester of clogestone, which, similarly was never marketed.^[2] Clogestone acetate produces chlormadinone acetate as an active metabolite.^[6]