Cloperidone

Cloperidone
Identifiers
	IUPAC name 3-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-1H-quinazoline-2,4-dione;
CAS Number	4052-13-5;
PubChem CID	10675;
ChemSpider	10225;
UNII	8FP5Y6U39R;
ChEMBL	ChEMBL2110792;
CompTox Dashboard (EPA)	DTXSID30193530 ;
Chemical and physical data
Formula	C21H23ClN4O2
Molar mass	398.89 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1CN(CCN1CCCN2C(=O)C3=CC=CC=C3NC2=O)C4=CC(=CC=C4)Cl;
	InChI InChI=1S/C21H23ClN4O2/c22-16-5-3-6-17(15-16)25-13-11-24(12-14-25)9-4-10-26-20(27)18-7-1-2-8-19(18)23-21(26)28/h1-3,5-8,15H,4,9-14H2,(H,23,28); Key:FXZJKVODWNYPKK-UHFFFAOYSA-N;

Cloperidone is a quinazolinedione derivative first reported in 1965 by Miles Laboratories, notable for its sedative and antihypertensive properties.^[1]^[2] Its pharmacological activity has been demonstrated in various animal models, including behavioral studies in dogs and cats, as well as motor coordination and locomotor activity assays in mice.^[2] Cloperidone is not an approved drug and appears to remain an experimental compound with no current clinical use.^[2]

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Identifiers

IUPAC name 3-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-1H-quinazoline-2,4-dione
CAS Number	4052-13-5
PubChem CID	10675
ChemSpider	10225
UNII	8FP5Y6U39R
ChEMBL	ChEMBL2110792
CompTox Dashboard (EPA)	DTXSID30193530
Chemical and physical data
Formula	C₂₁H₂₃ClN₄O₂
Molar mass	398.89 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1CN(CCN1CCCN2C(=O)C3=CC=CC=C3NC2=O)C4=CC(=CC=C4)Cl
InChI InChI=1S/C21H23ClN4O2/c22-16-5-3-6-17(15-16)25-13-11-24(12-14-25)9-4-10-26-20(27)18-7-1-2-8-19(18)23-21(26)28/h1-3,5-8,15H,4,9-14H2,(H,23,28) Key:FXZJKVODWNYPKK-UHFFFAOYSA-N