DDX42

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

ATP-dependent RNA helicase DDX42 is an enzyme that in humans is encoded by the DDX42 gene.[5][6]

AliasesDDX42, DDX42P, RHELP, RNAHP, SF3B8, SF3b125, DEAD-box helicase 42
End63,819,317 bp[1]
Quick facts Identifiers, Aliases ...
DDX42
Identifiers
AliasesDDX42, DDX42P, RHELP, RNAHP, SF3B8, SF3b125, DEAD-box helicase 42
External IDsOMIM: 613369; MGI: 1919297; HomoloGene: 49137; GeneCards: DDX42; OMA:DDX42 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007372
NM_203499

NM_028074

RefSeq (protein)

NP_031398
NP_987095

NP_082350
NP_001348569
NP_001348571
NP_001348572
NP_001348573

Location (UCSC)Chr 17: 63.77 – 63.82 MbChr 11: 106.22 – 106.25 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

This gene encodes a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Two transcript variants encoding the same protein have been identified for this gene.[6]

Interactions

DDX42 has been shown to interact with SF3B1.[7]

References

Further reading

Related Articles

Wikiwand AI