DMCM

Chemical compound From Wikipedia, the free encyclopedia

DMCM (methyl 6,7-dimethoxy-4-ethyl-β-carboline-3-carboxylate) is a drug from the β-carboline family that induces anxiety and convulsions by acting as a negative allosteric modulator of GABAA receptors — functionally opposite to benzodiazepines and related drugs which are positive allosteric modulators — and is used in scientific research for these properties to test new anxiolytic and anticonvulsant medications, respectively.[1][2][3][4] It has also been shown to produce analgesic effects in animals, which is thought to be the drug's induced panic reducing the perception of pain.[5]

Quick facts Names, Identifiers ...
DMCM
Names
Preferred IUPAC name
Methyl 4-ethyl-6,7-dimethoxy-9H-pyrido[3,4-b]indole-3-carboxylate
Other names
DMCM
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.220.168 Edit this at Wikidata
UNII
  • InChI=1S/C17H18N2O4/c1-5-9-15-10-6-13(21-2)14(22-3)7-11(10)19-12(15)8-18-16(9)17(20)23-4/h6-8,19H,5H2,1-4H3 ☒N
    Key: GADIKQPUNWAMEB-UHFFFAOYSA-N ☒N
  • CCC1=C2C3=CC(=C(C=C3NC2=CN=C1C(=O)OC)OC)OC
Properties
C17H18N2O4
Molar mass 314.336 g/mol
Boiling point 87 °C (189 °F; 360 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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