DNAI2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Dynein axonemal intermediate chain 2 also known as axonemal dynein intermediate chain 2, is a protein that in humans is encoded by the DNAI2 gene.[5][6]

AliasesDNAI2, CILD9, DIC2, dynein axonemal intermediate chain 2
End74,314,884 bp[1]
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DNAI2
Identifiers
AliasesDNAI2, CILD9, DIC2, dynein axonemal intermediate chain 2
External IDsOMIM: 605483; MGI: 2685574; HomoloGene: 11311; GeneCards: DNAI2; OMA:DNAI2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001172810
NM_023036
NM_001353167

NM_001034878

RefSeq (protein)

NP_001166281
NP_075462
NP_001340096

NP_001030050

Location (UCSC)Chr 17: 74.27 – 74.31 MbChr 11: 114.62 – 114.65 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene belongs to the dynein intermediate chain family, and is part of the dynein complex of respiratory cilia and sperm flagella.[5]

Clinical significance

Mutations in the DNAI2 gene are associated with primary ciliary dyskinesia.[7]

References

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