Dynein axonemal light chain 1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Dynein axonemal light chain 1, (LC1) is a protein that in humans is encoded by the DNAL1 gene.[5][6]

AliasesDNAL1, C14orf168, CILD16, dynein axonemal light chain 1, LC1
End73,703,732 bp[1]
Quick facts DNAL1, Identifiers ...
DNAL1
Identifiers
AliasesDNAL1, C14orf168, CILD16, dynein axonemal light chain 1, LC1
External IDsOMIM: 610062; MGI: 1921462; HomoloGene: 34623; GeneCards: DNAL1; OMA:DNAL1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001201366
NM_031427

NM_028821
NM_001346528

RefSeq (protein)

NP_001188295
NP_113615

NP_001333457
NP_083097

Location (UCSC)Chr 14: 73.64 – 73.7 MbChr 12: 84.16 – 84.19 Mb
PubMed search[3][4]
Wikidata
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Function

LC1 is a component of outer dynein arms, which contain the molecular motors for ATP-dependent cilia movement.[5][6]

Clinical significance

Mutations in the DNAL1 gene are associated with primary ciliary dyskinesia.[7]

References

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