DPH-362

DPH-362 is a simplified amitriptyline analog created by omission of the two-carbon dibenzosuberane bridge (the seven membered ring). The resulting compound still had activity in a test to explore TCA sodium channel blockers with analgesic properties.^[1][2]

Other namesPD129167

CAS Number

• 28916-83-8

PubChem CID

• 13465

ChemSpider

• 12888

Quick facts Clinical data, Other names ...

DPH-362

Clinical data
Other names	PD129167
Identifiers
IUPAC name N,N-dimethyl-4,4-diphenylbut-3-en-1-amine
CAS Number	28916-83-8
PubChem CID	13465
ChemSpider	12888
Chemical and physical data
Formula	C18H21N
Molar mass	251.373 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN(C)CCC=C(C1=CC=CC=C1)C2=CC=CC=C2
InChI InChI=InChI=1S/C18H21N/c1-19(2)15-9-14-18(16-10-5-3-6-11-16)17-12-7-4-8-13-17/h3-8,10-14H,9,15H2,1-2H3 Key:ZRPJJBLGKLVADE-UHFFFAOYSA-N

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It is based on previous structures such as Spasmolytic A29 (one of the active ingredients in Ketogan)^[3][4] and SKF-89976A.