DSN1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

DSN1, MIND kinetochore complex component, homolog (S. cerevisiae), also known as DSN1 or MIS13, is a protein which in humans encoded by the DSN1 gene.[5][6]

AliasesDSN1, C20orf172, KNL3, MIS13, dJ469A13.2, hKNL-3, DSN1 homolog, MIS12 kinetochore complex component, DSN1 component of MIS12 kinetochore complex
End36,773,818 bp[1]
Quick facts Identifiers, Aliases ...
DSN1
Identifiers
AliasesDSN1, C20orf172, KNL3, MIS13, dJ469A13.2, hKNL-3, DSN1 homolog, MIS12 kinetochore complex component, DSN1 component of MIS12 kinetochore complex
External IDsOMIM: 609175; MGI: 1914184; HomoloGene: 49806; GeneCards: DSN1; OMA:DSN1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001145315
NM_001145316
NM_001145317
NM_001145318
NM_024918

NM_025853

RefSeq (protein)

NP_001138787
NP_001138788
NP_001138789
NP_001138790
NP_079194

NP_080129

Location (UCSC)Chr 20: 36.75 – 36.77 MbChr 2: 156.84 – 156.85 Mb
PubMed search[3][4]
Wikidata
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Function

DSN1 along with MIS12, DC8, PMF1, CBX5, ZWINT is a component of the kinetochore-associated multiprotein complex which is required for correct chromosome alignment during the metaphase of cell mitosis.[6][7]

Interactions

DSN1 has been shown to interact with NSL1[8] and MIS12.[6][9]

References

Further reading

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