DTX1

DTX1
Identifiers
Aliases	DTX1, hDx-1, deltex 1, deltex E3 ubiquitin ligase 1, RNF140
External IDs	OMIM: 602582; MGI: 1352744; HomoloGene: 74522; GeneCards: DTX1; OMA:DTX1 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	113,098,028 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	120,849,992 bp
RNA expression pattern
	Top expressed in
	spleen; ; right frontal lobe; ; cingulate gyrus; ; anterior cingulate cortex; ; right hemisphere of cerebellum; ; nucleus accumbens; ; Brodmann area 9; ; amygdala; ; ganglionic eminence; ; prefrontal cortex;
	Top expressed in
	entorhinal cortex; ; mesenteric lymph nodes; ; perirhinal cortex; ; dentate gyrus of hippocampal formation granule cell; ; primary visual cortex; ; motor neuron; ; superior colliculus; ; cerebellar cortex; ; lumbar subsegment of spinal cord; ; Rostral migratory stream;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	SH3 domain binding; transcription coactivator activity; zinc ion binding; protein binding; ubiquitin protein ligase binding; metal ion binding; Notch binding; transferase activity;
Cellular component	cytoplasm; nucleus; nucleoplasm; cytosol; nuclear body;
Biological process	Notch signaling pathway; cell surface receptor signaling pathway; glial cell differentiation; transcription by RNA polymerase II; regulation of Notch signaling pathway; negative regulation of T cell differentiation; negative regulation of neuron differentiation; protein ubiquitination; transcription, DNA-templated; cellular response to leukemia inhibitory factor; positive regulation of nucleic acid-templated transcription;
	Sources:Amigo / QuickGO
Orthologs
	1840
	14357
	ENSG00000135144
	ENSMUSG00000029603
	Q86Y01
	Q61010
	NM_004416
	NM_008052
	NP_004407
	NP_032078
	Wikidata
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