DYNLT3

Protein-coding gene in humans From Wikipedia, the free encyclopedia

Dynein, light chain, Tctex-type 3, also known as DYNLT3, is a protein which in humans is encoded by the DYNLT3 gene.[5][6]

AliasesDYNLT3, RP3, TCTE1L, TCTEX1L, dynein light chain Tctex-type 3
End37,847,571 bp[1]
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DYNLT3
Identifiers
AliasesDYNLT3, RP3, TCTE1L, TCTEX1L, dynein light chain Tctex-type 3
External IDsOMIM: 300302; MGI: 1914367; HomoloGene: 21304; GeneCards: DYNLT3; OMA:DYNLT3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006520

NM_025975

RefSeq (protein)

NP_006511

NP_080251

Location (UCSC)Chr X: 37.84 – 37.85 MbChr X: 9.52 – 9.53 Mb
PubMed search[3][4]
Wikidata
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Function

DYNLT3 is a member of the dynein motor protein family. DYNLT3 binds to BUB3, a spindle checkpoint protein is present on kinetochores at prometaphase.[7] DYNLT3 can also function as a transcription regulator of Bcl-2 gene through binding to SATB1 in a dynein-independent manner.[8]

Interactions

DYNLT3 has been shown to interact with VDAC1.[9]

References

Further reading

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