DYX1C1

DNAAF4
Identifiers
Aliases	DNAAF4, CILD25, DYX1, DYXC1, EKN1, RD, DYX1C1, dyslexia susceptibility 1 candidate 1, dynein axonemal assembly factor 4
External IDs	OMIM: 608706; MGI: 1914935; HomoloGene: 12173; GeneCards: DNAAF4; OMA:DNAAF4 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	55,508,234 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	72,880,346 bp
RNA expression pattern
	Top expressed in
	bronchial epithelial cell; ; secondary oocyte; ; mucosa of paranasal sinus; ; testicle; ; olfactory zone of nasal mucosa; ; right uterine tube; ; gonad; ; right lobe of thyroid gland; ; epithelium of nasopharynx; ; left lobe of thyroid gland;
	Top expressed in
	spermatocyte; ; seminiferous tubule; ; saccule; ; morula; ; otic vesicle; ; embryo; ; spermatid; ; embryo; ; blastocyst; ; vestibular sensory epithelium;
	More reference expression data
	n/a
Gene ontology
Molecular function	estrogen receptor binding; protein binding;
Cellular component	nucleus; plasma membrane; cytoplasm; centrosome; cytosol; non-motile cilium; extracellular region;
Biological process	nervous system development; outer dynein arm assembly; regulation of intracellular estrogen receptor signaling pathway; regulation of proteasomal protein catabolic process; determination of left/right symmetry; inner dynein arm assembly; neuron migration; cilium movement; epithelial cilium movement involved in extracellular fluid movement; development of the heart;
	Sources:Amigo / QuickGO
Orthologs
	161582
	67685
	ENSG00000256061
	ENSMUSG00000092192
	Q8WXU2
	Q8R368
	NM_130810; NM_001033559; NM_001033560
	NM_001163725; NM_026314
	NP_001028731; NP_001028732; NP_570722
	NP_001157197; NP_080590
	Wikidata
View/Edit Human	View/Edit Mouse

Dyslexia susceptibility 1 candidate gene 1 protein is a protein that in humans is encoded by the DYX1C1 gene.^[5]^[6] This protein contains 420 amino acids with 3 tetratricopeptide repeat (TPR) domains, thought to mediate protein–protein interactions.