Daniel W. Nebert
American biomedical scientist and physician (born 1938)
From Wikipedia, the free encyclopedia
Daniel Walter Nebert is an American physician-scientist. He is a professor emeritus at the University of Cincinnati College of Medicine. His research has revolved around the central theme of gene–environment interactions.
- Wesleyan University (BA)
- University of Oregon Medical School (MS, MD)
- Discovery of the basic-helix/loop/helix per-Arnt-sim (bHLH/PAS), aryl hydrocarbon receptor (AHR)
- Standardizing gene nomenclature system, based on evolutionary divergence
- Discovery of the SLC39A8 gene encoding ZIP8 transporter of divalent cations
Daniel W. Nebert | |
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Nebert in 2004 | |
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| Spouse | Lucia Fung Jorge |
| Children | 6 |
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| Fields | Biomedical sciences, medicine |
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Education
Nebert completed a BA degree at Wesleyan University in 1960.[1] He went on to the five-year program at the University of Oregon Medical School; he completed a MS in biophysics and an MD in 1964.[1] Nebert had a pediatric internship and residency at the University of California, Los Angeles Health Sciences Center from 1964 to 1966.[1] He was a postdoctoral fellow at the National Cancer Institute from 1966 to 1968.[1]
Career
Nebert moved to the NICHD in 1968. He remained there until 1989, and served as section head and the chief of the Laboratory of Developmental Pharmacology.[1]
Nebert then moved to the University of Cincinnati Medical Center in December 1989, where he was hired as a professor of environmental health.[1][2] He also had an adjunct professor title in the Human Genetics Division, Department of Pediatrics and Molecular & Developmental Biology at Cincinnati Children's Hospital Medical Center beginning in 1991.[3] He remained at the University of Cincinnati until retiring as a professor emeritus in 2013.[1][2]
Nebert has published more than 670 papers in several scientific fields. In January 2025, Nebert's Google Scholar h-index was 140 with more than 82,500 citations.[4]
Awards and honors
Nebert was elected a Fellow of the American Association for the Advancement of Science in 1994, as a member of the medical sciences section.[5][6]
Selected publications
- Nebert DW, Gonzalez FJ. P450 genes: structure, evolution, and regulation. Annu Rev Biochem. 1987;56:945-93. PMID: 3304150
- Zhang G, Nebert DW. Personalized medicine: Genetic risk prediction of drug response. Pharmacol Ther. 2017 Jul;175:75-90. PMID: 28213088
- Nebert DW. Aryl hydrocarbon receptor (AHR): "pioneer member" of the basic-helix/loop/helix per-Arnt-sim (bHLH/PAS) family of "sensors" of foreign and endogenous signals. Prog Lipid Res. 2017 Jul;67:38-57. PMID: 28606467
- Nebert DW, Liu Z. SLC39A8 gene encoding a metal ion transporter: discovery and bench to bedside. Hum Genomics. 2019 Sep 14;13(Suppl 1):51. PMID: 31521203
