Dazadrol

Dazadrol is a synthetic antidepressant developed by Schering Corp in the late 1960s. It acts primarily as a noradrenaline reuptake inhibitor, increasing concentrations of noradrenaline in the synaptic cleft, which is believed to underlie its antidepressant effects.^[1][2][3]

Other namesSch 12650

CAS Number

• 47029-84-5 25387-70-6

PubChem CID

• 32940

ChemSpider

• 30497

Quick facts Clinical data, Other names ...

Dazadrol

Clinical data
Other names	Sch 12650
Identifiers
IUPAC name (4-chlorophenyl)-(4,5-dihydro-1H-imidazol-2-yl)-pyridin-2-ylmethanol
CAS Number	47029-84-5 25387-70-6
PubChem CID	32940
ChemSpider	30497
UNII	9U27285V5R
ChEMBL	ChEMBL2110607
CompTox Dashboard (EPA)	DTXSID60866124
ECHA InfoCard	100.051.158
Chemical and physical data
Formula	C15H14ClN3O
Molar mass	287.75 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CN=C(N1)C(C2=CC=C(C=C2)Cl)(C3=CC=CC=N3)O
InChI InChI=1S/C15H14ClN3O/c16-12-6-4-11(5-7-12)15(20,14-18-9-10-19-14)13-3-1-2-8-17-13/h1-8,20H,9-10H2,(H,18,19) Key:DITYEPYMBCHKLF-UHFFFAOYSA-N

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Dazadrol is classified as a pyridinemethanol derivative and has been studied for its impact on neurological function and mood. In addition to its antidepressant activity, preclinical studies in rats have shown that it inhibits both basal and induced gastric acid secretion, indicating potential gastrointestinal effects.^[1][3][4][2]