Delucemine

Chemical compound From Wikipedia, the free encyclopedia

Delucemine (NPS-1506) is a drug which acts as an NMDA antagonist and a serotonin reuptake inhibitor, and has neuroprotective effects.[1][2] It was originally investigated for the treatment of stroke and in 2004 was studied as a potential antidepressant.[3][4][5]

ATC code
  • none
Quick facts Clinical data, ATC code ...
Delucemine
Clinical data
ATC code
  • none
Identifiers
  • 3,3-Bis(3-fluorophenyl)-N-methylpropan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H17F2N
Molar mass261.316 g·mol−1
3D model (JSmol)
  • CNCCC(C1=CC(=CC=C1)F)C2=CC(=CC=C2)F
  • InChI=1S/C16H17F2N/c1-19-9-8-16(12-4-2-6-14(17)10-12)13-5-3-7-15(18)11-13/h2-7,10-11,16,19H,8-9H2,1H3 ☒N
  • Key:MUGNLPWYHGOJEG-UHFFFAOYSA-N ☒N
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Origin

The structure of delucemine is based on argiotoxin 636, a NMDA antagonist isolated from the venom of Argiope aurantia.[6][7][8]

See also

References

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