Ethylmorphine

Opioid analgesic and antitussive drug From Wikipedia, the free encyclopedia

Ethylmorphine (also known as codethyline, dionine, and ethyl morphine) is an opioid analgesic and antitussive.[4][5][6][7][8][9]

Trade namesCosylan, Diolan, Dionina, Diosan, Solvipect, Trachyl
AHFS/Drugs.comInternational Drug Names
Routes of
administrationOral
ATC code
Quick facts Clinical data, Trade names ...
Ethylmorphine
Structural formula
Ball-and-stick model
Clinical data
Trade namesCosylan, Diolan, Dionina, Diosan, Solvipect, Trachyl
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Oral
ATC code
Legal status
Legal status
Pharmacokinetic data
MetabolismHepatic, specifically CYP2D6[3]
Identifiers
  • 7,8-didehydro-4,5-α-epoxy- 3-ethoxy-17-methylmorphinan-6-α-ol
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.000.883 Edit this at Wikidata
Chemical and physical data
FormulaC19H23NO3
Molar mass313.397 g·mol−1
3D model (JSmol)
  • O[C@H]2\C=C/[C@H]5[C@@H]4N(CC[C@@]51c3c(O[C@H]12)c(OCC)ccc3C4)C
  • InChI=1S/C19H23NO3/c1-3-22-15-7-4-11-10-13-12-5-6-14(21)18-19(12,8-9-20(13)2)16(11)17(15)23-18/h4-7,12-14,18,21H,3,8-10H2,1-2H3/t12-,13+,14-,18-,19-/m0/s1 checkY
  • Key:OGDVEMNWJVYAJL-LEPYJNQMSA-N checkY
  (verify)
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Side effects

Adverse effects are similar to other opioids and include drowsiness, constipation, vertigo, nausea, vomiting, and respiratory depression. Contraindications include asthma, respiratory insufficiency, and age under 8. Ethylmorphine may affect the user's ability to drive and operate heavy machinery, and may cause chemical dependence or addiction at high doses.[10]

Society and culture

Ethylmorphine was first marketed in France in 1953 by Houde, and in Norway and Spain in 1960. It is not marketed in the United States and is a Schedule II controlled substance.[10][11]

See also

References

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