Dopastin

Dopastin is a chemical compound produced by the bacteria Pseudomonas No. BAC-125.^[2] It was first isolated and characterized in 1972. It is an inhibitor of the enzyme dopamine β-hydroxylase.^[3]

Quick facts Names, Identifiers ...

Dopastin

Names
Preferred IUPAC name (2E)-N-{(2S)-2-[Hydroxy(nitroso)amino]-3-methylbutyl}but-2-enamide
Identifiers
CAS Number	37134-80-8 Y
3D model (JSmol)	Interactive image
ChemSpider	4939169
PubChem CID	6434226
UNII	F8KR5E0EHC Y
CompTox Dashboard (EPA)	DTXSID001029849
InChI InChI=1S/C9H17N3O3/c1-4-5-9(13)10-6-8(7(2)3)12(15)11-14/h4-5,7-8,15H,6H2,1-3H3,(H,10,13)/b5-4+/t8-/m1/s1 Key: FJUBKTNNXRFHFD-WTSVBCDHSA-N InChI=1/C9H17N3O3/c1-4-5-9(13)10-6-8(7(2)3)12(15)11-14/h4-5,7-8,15H,6H2,1-3H3,(H,10,13)/b5-4+/t8-/m1/s1 Key: FJUBKTNNXRFHFD-WTSVBCDHBR
SMILES O=C(NC[C@@H](N(O)N=O)C(C)C)/C=C/C
Properties
Chemical formula	C9H17N3O3
Molar mass	215.253 g·mol−1
Melting point	116 to 119 °C (241 to 246 °F; 389 to 392 K)[1]
Acidity (pKa)	5.1[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Close

Dopastin can be prepared synthetically from L-valinol.^[4]