Diprophylline

Diprophylline (INN)^[1] or dyphylline (USAN) (trade names Dilor, Lufyllin) is a xanthine derivative with bronchodilator and vasodilator effects. It is used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. It acts as an adenosine receptor antagonist and phosphodiesterase inhibitor.^[2][3]

Trade namesLufyllin

Other names7-(2,3-Dihydroxy-propyl)theophylline

AHFS/Drugs.comConsumer Drug Information

MedlinePlusa682494

Quick facts Clinical data, Trade names ...

Diprophylline

Clinical data
Trade names	Lufyllin
Other names	7-(2,3-Dihydroxy-propyl)theophylline
AHFS/Drugs.com	Consumer Drug Information
MedlinePlus	a682494
Routes of administration	By mouth
ATC code	R03DA01 (WHO)
Legal status
Legal status	US: ℞-only
Identifiers
IUPAC name 7-(2,3-Dihydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
CAS Number	479-18-5 Y
PubChem CID	3182
IUPHAR/BPS	7070
DrugBank	DB00651 Y
ChemSpider	3070 Y
UNII	263T0E9RR9
KEGG	D00691 Y
ChEBI	CHEBI:4728 Y
ChEMBL	ChEMBL1752 Y
CompTox Dashboard (EPA)	DTXSID6022975
ECHA InfoCard	100.006.843
Chemical and physical data
Formula	C10H14N4O4
Molar mass	254.246 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C2N(c1ncn(c1C(=O)N2C)CC(O)CO)C
InChI InChI=1S/C10H14N4O4/c1-12-8-7(9(17)13(2)10(12)18)14(5-11-8)3-6(16)4-15/h5-6,15-16H,3-4H2,1-2H3 Y Key:KSCFJBIXMNOVSH-UHFFFAOYSA-N Y
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