EA-2192
Chemical compound
From Wikipedia, the free encyclopedia
EA-2192 is an extremely toxic degradation product of the VX, a very potent nerve agent.[1][2] It is a white solid that is very soluble and stable in water.
| Names | |
|---|---|
| Preferred IUPAC name
S-{2-[Di(propan-2-yl)amino]ethyl} methylphosphonothioate | |
| Other names
Diisopropylaminoethyl methyl thiolophosphonate | |
| Identifiers | |
3D model (JSmol) |
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| ChemSpider | |
PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C9H22NO2PS | |
| Molar mass | 239.31 g·mol−1 |
| Appearance | White solid |
| Very soluble | |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards |
Extremely toxic |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
630 μg/kg (Rat, oral) 18 μg/kg (Rat, iv) 50 μg/kg (Mouse, iv) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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EA-2192 is an extremely potent acetylcholinesterase inhibitor. It is almost as toxic as VX itself, but it is inferior in dermal penetration.[3][4]
EA-2192 instantly ages acetylcholinesterase as it is the dealkylated form of VX and can also not be reversed with common oxime reactivators.[5]

