ECT2
Gene of the species Homo sapiens
From Wikipedia, the free encyclopedia
Protein ECT2 is a protein that in humans is encoded by the ECT2 gene.[4][5][6]
External IDsOMIM: 600586; MGI: 95281; HomoloGene: 7298; GeneCards: ECT2; OMA:ECT2 - orthologs
Function
The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.[6]
