EEF1B2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Elongation factor 1-beta is a protein that in humans is encoded by the EEF1B2 gene.[5][6]

PDBOrtholog search: PDBe RCSB
AliasesEEF1B2, EEF1B, EEF1B1, EF1B, eukaryotic translation elongation factor 1 beta 2
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EEF1B2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesEEF1B2, EEF1B, EEF1B1, EF1B, eukaryotic translation elongation factor 1 beta 2
External IDsOMIM: 600655; MGI: 1929520; HomoloGene: 1480; GeneCards: EEF1B2; OMA:EEF1B2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_021121
NM_001037663
NM_001959

NM_018796

RefSeq (protein)

NP_001032752
NP_001950
NP_066944

NP_061266

Location (UCSC)Chr 2: 206.16 – 206.16 MbChr 1: 63.22 – 63.22 Mb
PubMed search[3][4]
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Function

This gene encodes a translation elongation factor. The protein is a guanine nucleotide exchange factor involved in the transfer of aminoacylated tRNAs to the ribosome. Alternative splicing results in three transcript variants which differ only in the 5' UTR.[6]

Interactions

EEF1B2 has been shown to interact with EEF1G[7][8] and HARS.[9]

References

Further reading

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