EEF1D
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
Elongation factor 1-delta is a protein that in humans is encoded by the EEF1D gene.[5]
External IDsOMIM: 130592; MGI: 1913906; HomoloGene: 23404; GeneCards: EEF1D; OMA:EEF1D - orthologs
| EEF1D | |||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| |||||||||||||||||||||||||||||||
| Identifiers | |||||||||||||||||||||||||||||||
| Aliases | EEF1D, EF-1D, EF1D, FP1047, eukaryotic translation elongation factor 1 delta | ||||||||||||||||||||||||||||||
| External IDs | OMIM: 130592; MGI: 1913906; HomoloGene: 23404; GeneCards: EEF1D; OMA:EEF1D - orthologs | ||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||
| Wikidata | |||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||
Function
This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit functions as guanine nucleotide exchange factor. It is reported that this subunit interacts with HIV-1 Tat, and thus it represses the translation of host-cell, but not HIV-1, mRNAs. Several alternatively spliced transcript variants have been found for this gene, however, the full length nature of only two variants has been determined.[6]
