Ephrin B1

EFNB1
Identifiers
Aliases	EFNB1, CFND, CFNS, EFB1, EFL3, EPLG2, Elk-L, LERK2, ephrin B1
External IDs	OMIM: 300035; MGI: 102708; HomoloGene: 3263; GeneCards: EFNB1; OMA:EFNB1 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	68,842,160 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	98,192,597 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; right lung; ; ganglionic eminence; ; mucosa of transverse colon; ; skin of abdomen; ; skin of leg; ; upper lobe of left lung; ; tibial nerve; ; apex of heart; ; ectocervix;
	Top expressed in
	ventricular zone; ; Ileal epithelium; ; external carotid artery; ; lumbar spinal ganglion; ; internal carotid artery; ; Rostral migratory stream; ; renal corpuscle; ; lip; ; yolk sac; ; gastrula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; ephrin receptor binding; protein tyrosine kinase activity;
Cellular component	integral component of membrane; nucleus; extracellular exosome; membrane; membrane raft; integral component of plasma membrane; synapse; cytoplasm; plasma membrane;
Biological process	positive regulation of T cell proliferation; nervous system development; cell-cell signaling; T cell costimulation; multicellular organism development; neural crest cell migration; cell differentiation; cell adhesion; embryonic pattern specification; axon guidance; ephrin receptor signaling pathway; peptidyl-tyrosine phosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	1947
	13641
	ENSG00000090776
	ENSMUSG00000031217
	P98172
	P52795
	NM_004429
	NM_010110
	NP_004420
	NP_034240
	Wikidata
View/Edit Human	View/Edit Mouse

Ephrin B1 is a protein that in humans is encoded by the EFNB1 gene.^[5]^[6] It is a member of the ephrin family. The encoded protein is a type I membrane protein and a ligand of Eph-related receptor tyrosine kinases. It may play a role in cell adhesion and function in the development or maintenance of the nervous system.^[7]