EIF2B4

Translation initiation factor eIF-2B subunit delta is a protein that in humans is encoded by the EIF2B4 gene.^[5][6][7]

AliasesEIF2B4, EIF-2B, EIF2B, EIF2Bdelta, eukaryotic translation initiation factor 2B subunit delta

External IDsOMIM: 606687; MGI: 95300; HomoloGene: 5976; GeneCards: EIF2B4; OMA:EIF2B4 - orthologs

Chr.Chromosome 2 (human)^[1]

End27,370,338 bp^[1]

Quick facts Identifiers, Aliases ...

EIF2B4
Identifiers
Aliases	EIF2B4, EIF-2B, EIF2B, EIF2Bdelta, eukaryotic translation initiation factor 2B subunit delta
External IDs	OMIM: 606687; MGI: 95300; HomoloGene: 5976; GeneCards: EIF2B4; OMA:EIF2B4 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2p23.3 Start 27,364,352 bp[1] End 27,370,338 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 B1 Start 31,344,902 bp[2] End 31,350,774 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas left testis right testis muscle layer of sigmoid colon sural nerve gingival epithelium anterior pituitary skin of abdomen mucosa of transverse colon skin of leg Top expressed in primitive streak temporal muscle primary oocyte digastric muscle hair follicle sternocleidomastoid muscle triceps brachii muscle muscle of thigh vastus lateralis muscle motor neuron More reference expression data BioGPS More reference expression data
Gene ontology Molecular function guanyl-nucleotide exchange factor activity protein binding translation initiation factor binding translation initiation factor activity Cellular component cytoplasm cytosol eukaryotic translation initiation factor 2B complex Biological process response to peptide hormone response to heat response to glucose cell metabolism ovarian follicle development myelination oligodendrocyte development regulation of translation translational initiation protein biosynthesis T cell receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8890 13667 Ensembl ENSG00000115211 ENSMUSG00000029145 UniProt Q9UI10 Q61749 RefSeq (mRNA) NM_001034116 NM_015636 NM_172195 NM_001318965 NM_001318966 NM_001318967 NM_001318968 NM_001318969 NM_001127355 NM_001127356 NM_010122 RefSeq (protein) NP_001029288 NP_001305894 NP_001305895 NP_001305896 NP_001305897 NP_001305898 NP_056451 NP_751945 NP_001305896.1 NP_001120827 NP_001120828 NP_034252 Location (UCSC) Chr 2: 27.36 – 27.37 Mb Chr 5: 31.34 – 31.35 Mb PubMed search [3] [4]
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