EIF4EBP3

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Eukaryotic translation initiation factor 4E-binding protein 3 is a protein that in humans is encoded by the EIF4EBP3 gene.[5][6]

AliasesEIF4EBP3, 4E-BP3, 4EBP3, eukaryotic translation initiation factor 4E binding protein 3
End140,549,576 bp[1]
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EIF4EBP3
Identifiers
AliasesEIF4EBP3, 4E-BP3, 4EBP3, eukaryotic translation initiation factor 4E binding protein 3
External IDsOMIM: 603483; MGI: 1270847; HomoloGene: 37841; GeneCards: EIF4EBP3; OMA:EIF4EBP3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003732

NM_201256

RefSeq (protein)

NP_003723

NP_957708

Location (UCSC)Chr 5: 140.55 – 140.55 MbChr 18: 36.8 – 36.8 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a member of the EIF4EBP family which derives its name from proteins that bind to eukaryotic initiation factor 4E and that prevent its assembly into EIF4F. Co-transcription of this gene and the neighboring upstream gene (MASK) generates a transcript (MASK-BP3) which encodes a fusion protein composed of the MASK protein sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments.[6]

Interactions

EIF4EBP3 has been shown to interact with EIF4E.[5][7]

References

Further reading

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