ELK4

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

ETS domain-containing protein Elk-4 is a protein that in humans is encoded by the ELK4 gene.[5][6][7]

PDBOrtholog search: PDBe RCSB
AliasesELK4, SAP1, ETS transcription factor, ETS transcription factor ELK4
Quick facts Available structures, PDB ...
ELK4
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesELK4, SAP1, ETS transcription factor, ETS transcription factor ELK4
External IDsOMIM: 600246; MGI: 102853; HomoloGene: 1492; GeneCards: ELK4; OMA:ELK4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001973
NM_021795

RefSeq (protein)

NP_001964
NP_068567
NP_068567.1

Location (UCSC)Chr 1: 205.6 – 205.63 MbChr 1: 131.94 – 131.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is phosphorylated by the kinases, MAPK1 and MAPK8. Several transcript variants have been described for this gene.[7]

Interactions

ELK4 has been shown to interact with:

References

Further reading

Related Articles

Wikiwand AI