ERO1L

ERO1A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3AHQ, 3AHR
Identifiers
Aliases	ERO1A, ERO1-alpha, ERO1LA, ERO1-L, ERO1-L-alpha, ERO1L, Ero1alpha, endoplasmic reticulum oxidoreductase alpha, endoplasmic reticulum oxidoreductase 1 alpha
External IDs	OMIM: 615435; MGI: 1354385; HomoloGene: 49392; GeneCards: ERO1A; OMA:ERO1A - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	52,695,900 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	45,556,228 bp
RNA expression pattern
	Top expressed in
	oral cavity; ; buccal mucosa cell; ; mucosa of pharynx; ; body of tongue; ; pericardium; ; tonsil; ; gums; ; amniotic fluid; ; islet of Langerhans; ; vena cava;
	Top expressed in
	cumulus cell; ; epithelium of stomach; ; pyloric antrum; ; mucous cell of stomach; ; decidua; ; gastrula; ; granulocyte; ; hair follicle; ; epithelium of small intestine; ; tail of embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; protein binding; oxidoreductase activity; protein-disulfide reductase activity; protein disulfide isomerase activity; disulfide oxidoreductase activity;
Cellular component	endoplasmic reticulum lumen; membrane; intracellular membrane-bounded organelle; dendrite; endoplasmic reticulum; endoplasmic reticulum membrane;
Biological process	release of sequestered calcium ion into cytosol; 4-hydroxyproline metabolic process; extracellular matrix organization; protein maturation by protein folding; cell redox homeostasis; response to endoplasmic reticulum stress; chaperone cofactor-dependent protein refolding; endoplasmic reticulum unfolded protein response; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; protein folding; brown fat cell differentiation; cellular response to hypoxia; response to temperature stimulus; apoptotic process; protein folding in endoplasmic reticulum; cellular response to oxidative stress;
	Sources:Amigo / QuickGO
Orthologs
	30001
	50527
	ENSG00000197930
	ENSMUSG00000021831
	Q96HE7
	Q8R180
	NM_014584
	NM_015774
NP_055399; NP_001369393; NP_001369394; NP_001369395; NP_001369396;
	NP_001369397; NP_001369398; NP_001369399; NP_001369400; NP_001369401; NP_001369402; NP_001369403; NP_001369404; NP_001369405
	NP_056589
	Wikidata
View/Edit Human	View/Edit Mouse

ERO1-like protein alpha is a protein that in humans is encoded by the ERO1L gene.^[5]^[6]

PDBOrtholog search: PDBe RCSB

AliasesERO1A, ERO1-alpha, ERO1LA, ERO1-L, ERO1-L-alpha, ERO1L, Ero1alpha, endoplasmic reticulum oxidoreductase alpha, endoplasmic reticulum oxidoreductase 1 alpha

External IDsOMIM: 615435; MGI: 1354385; HomoloGene: 49392; GeneCards: ERO1A; OMA:ERO1A - orthologs

Chr.Chromosome 14 (human)^[1]

Quick facts ERO1A, Available structures ...

Close

[5]

[6]

[1]

[2]

[3]

[4]

ERO1L

Interactions

References

Further reading

Related Articles

Related Articles

"ERp44, a novel endoplasmic reticulum folding assistant of the thioredoxin family"

"Manipulation of oxidative protein folding and PDI redox state in mammalian cells"

"The CXXCXXC motif determines the folding, structure and stability of human Ero1-Lalpha"

"Unfolded cholera toxin is transferred to the ER membrane and released from protein disulfide isomerase upon oxidation by Ero1"

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment"

"Thiol-mediated protein retention in the endoplasmic reticulum: the role of ERp44"