ETV4

ETV4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4CO8, 4UUV
Identifiers
Aliases	ETV4, E1A-F, E1AF, PEA3, PEAS3, ETS variant 4, ETS variant transcription factor 4
External IDs	OMIM: 600711; MGI: 99423; HomoloGene: 1504; GeneCards: ETV4; OMA:ETV4 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	43,579,620 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	101,676,197 bp
RNA expression pattern
	Top expressed in
	gonad; ; pituitary gland; ; testicle; ; anterior pituitary; ; mucosa of pharynx; ; pericardium; ; nipple; ; sural nerve; ; gallbladder; ; skin of limb;
	Top expressed in
	palate; ; soft palate; ; tail of embryo; ; cardiac muscle tissue of left ventricle; ; lip; ; palatoglossus muscle; ; epiblast; ; extensor digitorum longus muscle; ; urethra; ; tongue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleoplasm; nucleolus; nucleus;
Biological process	cell differentiation; regulation of transcription, DNA-templated; transcription, DNA-templated; transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	2118
	18612
	ENSG00000175832
	ENSMUSG00000017724
	P43268
	P28322
NM_001079675; NM_001261437; NM_001261438; NM_001261439; NM_001986;
	NM_001369366; NM_001369367; NM_001369368
	NM_008815; NM_001316365; NM_001316366
NP_001073143; NP_001248366; NP_001248367; NP_001248368; NP_001977;
	NP_001356295; NP_001356296; NP_001356297
	NP_001303294; NP_001303295; NP_032841
	Wikidata
View/Edit Human	View/Edit Mouse

ETS translocation variant 4 (ETV4), also known as polyoma enhancer activator 3 (PEA3), is a member of the PEA3 subfamily of Ets transcription factors.^[5]^[6]^[7]