EZH1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Histone-lysine N-methyltransferase EZH1 is an enzyme that in humans is encoded by the EZH1 gene.[5][6]

AliasesEZH1, KMT6B, enhancer of zeste 1 polycomb repressive complex 2 subunit
End42,745,049 bp[1]
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EZH1
Identifiers
AliasesEZH1, KMT6B, enhancer of zeste 1 polycomb repressive complex 2 subunit
External IDsOMIM: 601674; MGI: 1097695; HomoloGene: 20458; GeneCards: EZH1; OMA:EZH1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001991
NM_001321079
NM_001321081
NM_001321082

NM_007970

RefSeq (protein)

NP_001308008
NP_001308010
NP_001308011
NP_001982

Location (UCSC)Chr 17: 42.7 – 42.75 MbChr 11: 101.08 – 101.12 Mb
PubMed search[3][4]
Wikidata
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Function

In mice, EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair.[7] EZH1 also complements EZH2 in maintaining stem cell identity and executing pluripotency.[8]


References

Further reading

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