Eckol

Eckol
	Chemical structure of eckol
Names
	Preferred IUPAC name 4-(3,5-Dihydroxyphenoxy)oxanthrene-1,3,6,8-tetrol
	Other names 1-(3,5-Dihydroxyphenoxy)-2,4,7,9-tetrahydroxydibenzo-1,4-dioxin
Identifiers
CAS Number	88798-74-7 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:65819 ;
ChEMBL	ChEMBL471187 ;
ChemSpider	128740 ;
PubChem CID	145937;
UNII	4A5E8354UB ;
CompTox Dashboard (EPA)	DTXSID40237333 ;
	InChI InChI=1S/C18H12O9/c19-7-1-8(20)3-10(2-7)25-16-12(23)6-13(24)17-18(16)27-15-11(22)4-9(21)5-14(15)26-17/h1-6,19-24H Key: PCZZRBGISTUIOA-UHFFFAOYSA-N ; InChI=1/C18H12O9/c19-7-1-8(20)3-10(2-7)25-16-12(23)6-13(24)17-18(16)27-15-11(22)4-9(21)5-14(15)26-17/h1-6,19-24H Key: PCZZRBGISTUIOA-UHFFFAOYAJ;
	SMILES C1=C(C=C(C=C1O)OC2=C(C=C(C3=C2OC4=C(C=C(C=C4O3)O)O)O)O)O;
Properties
Chemical formula	C18H12O9
Molar mass	372.285 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Eckol is a phlorotannin isolated from brown algae in the family Lessoniaceae such as species in the genus Ecklonia^[1] such as E. cava^[2] or E. kurome^[3] or in the genus Eisenia such as Eisenia bicyclis.^[4]

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The molecule possesses a dibenzo-p-dioxin skeleton and a phloroglucinol component. The molecule can also be viewed as a phloroglucinol trimer.^[5]

It exhibits an antiplasmin inhibitory effect^[3] and a radioprotective effect in a mouse model.^[1]^[6] It also exhibits an in vitro cytoprotective effect against oxidative stress in Chinese hamster lung fibroblasts.^[2] It also shows antithrombotic and profibrinolytic activities.^[4]

References