Eprobemide

Chemical compound From Wikipedia, the free encyclopedia

Eprobemide (INN) is a pharmaceutical drug that was used as an antidepressant in Russia (under the brand name Бефол/Befol).[1] It is a non-competitive reversible inhibitor of monoamine oxidase A[2][3] that exhibits selective action on serotonin deamination.[4] Eprobemide differs from moclobemide only in the linker that connects the morpholine fragment with the chlorobenzamide — moclobemide has two carbon atoms while eprobemide has three. Its registration was cancelled on December 30, 2003.[5]

Other namesBefol
Legal status
  • In general: ℞ (Prescription only)
Quick facts Clinical data, Trade names ...
Eprobemide
Clinical data
Trade namesBefol (RU)
Other namesBefol
Routes of
administration
Oral
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • 4-Chloro-N-[3-(4-morpholinyl)propyl]benzamide
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H19ClN2O2
Molar mass282.77 g·mol−1
3D model (JSmol)
  • C1COCCN1CCCNC(=O)C2=CC=C(C=C2)Cl
  • InChI=1S/C14H19ClN2O2/c15-13-4-2-12(3-5-13)14(18)16-6-1-7-17-8-10-19-11-9-17/h2-5H,1,6-11H2,(H,16,18)
  • Key:YYFGRAGNYHYWEZ-UHFFFAOYSA-N
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References

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