Erika Crouch

Crouch received her B.S. from Washington State University in 1972.^[1] Crouch earned her Ph.D. in 1978 and then her M.D. in 1979, both from the University of Washington. She was a postdoctoral fellow and then a resident in anatomic pathology at the University of Washington. She completed a fellowship in pulmonary pathology at the University of British Columbia as a Parker B. Francis Fellow.^[2] In 1983 Crouch joined the Washington University School of Medicine faculty, and as of 2024 she is the Carol B. and Jerome T. Loeb Professor of Medical Education.^[3]

Crouch is known for her research in collectins, a carbohydrate binding protein that is involved in the immune system.^[4] She identified CP4, a novel secreted collagenous protein,^[5] and went on to determine its molecular structure.^[6] Working with John Heuser, she examined a surfactant protein, SP-D,^[7][8] and researched the interactions between SP-D and influenza A virus.^[9] She has also used structure-function analysis via crystallographic analysis and site-directed mutagenesis.^[10]

• Crouch, E. (1990-10-01). "Pathobiology of pulmonary fibrosis". American Journal of Physiology. Lung Cellular and Molecular Physiology. 259 (4): L159–L184. doi:10.1152/ajplung.1990.259.4.L159. ISSN 1040-0605. PMID 2221080.
• Kuan, S F; Rust, K; Crouch, E (1992-07-01). "Interactions of surfactant protein D with bacterial lipopolysaccharides. Surfactant protein D is an Escherichia coli-binding protein in bronchoalveolar lavage". Journal of Clinical Investigation. 90 (1): 97–106. doi:10.1172/JCI115861. ISSN 0021-9738. PMC 443067. PMID 1634623.
• Crouch, Erika; Hartshorn, Kevan; Ofek, Itzhak (2000). "Collectins and pulmonary innate immunity". Immunological Reviews. 173 (1): 52–65. doi:10.1034/j.1600-065X.2000.917311.x. ISSN 0105-2896.
• Crouch, Erika; Wright, Jo Rae (2001). "Surfactant Proteins A and D and Pulmonary Host Defense". Annual Review of Physiology. 63 (1): 521–554. doi:10.1146/annurev.physiol.63.1.521. ISSN 0066-4278. PMID 11181966.