Ethylone

Chemical compound From Wikipedia, the free encyclopedia

Ethylone, also known as 3,4-methylenedioxy-N-ethylcathinone (MDEC, βk-MDEA), is a recreational designer drug of the phenethylamine, amphetamine, and cathinone chemical classes.[1] It is the β-keto analogue of MDEA ("Eve"). Ethylone has only a short history of human use and is reported to be less potent than its relative methylone.[citation needed] In the United States, it began to be found in cathinone products in late 2011.[4]

Other names3,4-Methylenedioxy-N-ethylcathinone; MDEC; βk-MDEA
Pregnancy
category
  • N (US)
Quick facts Clinical data, Other names ...
Ethylone
Clinical data
Other names3,4-Methylenedioxy-N-ethylcathinone; MDEC; βk-MDEA
Pregnancy
category
  • N (US)
Routes of
administration
Oral[1]
Drug classSerotonin–norepinephrine–dopamine releasing agent; Entactogen
ATC code
  • None
Legal status
Legal status
Pharmacokinetic data
Duration of action2–4 hours[1]
Identifiers
  • (RS)-1-(1,3-benzodioxol-5-yl)-2-(ethylamino)propan-1-one
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC12H15NO3
Molar mass221.256 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
  • CC(NCC)C(=O)c1ccc2OCOc2c1
  • InChI=1S/C12H15NO3/c1-3-13-8(2)12(14)9-4-5-10-11(6-9)16-7-15-10/h4-6,8,13H,3,7H2,1-2H3 ☒N
  • Key:MJEMIOXXNCZZFK-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)
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Very little data exists about the pharmacological properties, metabolism, and toxicity of ethylone, and although several ethylone-related deaths have been reported, the cause of death was not due to ingestion of ethylone.[4]

Interactions

Pharmacology

Pharmacokinetics

Analysis of human and rat urine for the metabolites of bk-amphetamines suggested that ethylone was degraded in the following metabolic steps:[5]

  1. N-deethylation to the primary amine.
  2. Reduction of the keto moiety to the respective alcohol.

Society and culture

As of October 2015 Ethylone is a controlled substance in China.[6]

See also

References

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