Etripamil

Medication From Wikipedia, the free encyclopedia

Etripamil, sold under the brand name Cardamyst, is a medication used for the treatment of paroxysmal supraventricular tachycardia.[1] It is a calcium channel blocker.[1] It is used as a nasal spray.[1]

Trade namesCardamyst
Other namesMSP-2017
License data
Quick facts Clinical data, Trade names ...
Etripamil
Clinical data
Trade namesCardamyst
Other namesMSP-2017
AHFS/Drugs.comcardamyst
License data
Routes of
administration
Intranasal
Drug classCalcium channel blocker
ATC code
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC27H36N2O4
Molar mass452.595 g·mol−1
3D model (JSmol)
  • COC(=O)C1=CC(CCN(C)CCC[C@](C#N)(C(C)C)C2=CC=C(OC)C(OC)=C2)=CC=C1
  • InChI=1S/C27H36N2O4/c1-20(2)27(19-28,23-11-12-24(31-4)25(18-23)32-5)14-8-15-29(3)16-13-21-9-7-10-22(17-21)26(30)33-6/h7,9-12,17-18,20H,8,13-16H2,1-6H3/t27-/m0/s1
  • Key:VAZNEHLGJGSQEL-MHZLTWQESA-N
  • Key:JHOAIMAMBNLIMD-YCBFMBTMSA-N
Close

Etripamil was approved for medical use in the United States in December 2025.[2]

Medical uses

Etripamil is indicated for the conversion of acute symptomatic episodes of paroxysmal supraventricular tachycardia to sinus rhythm.[1][3][4]

Pharmacology

Mechanism of action

Etripamil is a voltage-dependent L-type calcium channel inhibitor.[3]

Society and culture

Etripamil was approved for medical use in the United States in December 2025.[2]

Names

Etripamil is the international nonproprietary name.[5]

Etripamil is sold under the brand name Cardamyst.[1]

References

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