Exodeoxyribonuclease (lambda-induced)
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Exodeoxyribonuclease (lambda-induced) (EC 3.1.11.3, lambda exonuclease, phage lambda-induced exonuclease, Escherichia coli exonuclease IV, E. coli exonuclease IV, exodeoxyribonuclease IV, exonuclease IV) is an exonuclease.[1][2] This enzyme catalyses the following chemical reaction
- Exonucleolytic cleavage in the 5′- to 3′-direction to yield nucleoside 5′-phosphates
| Exodeoxyribonuclease (lambda-induced) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.11.3 | ||||||||
| CAS no. | 37367-70-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme has preference for double-stranded DNA (dsDNA). This means that it degrades a single strand of dsDNA, primarily any strand which has a phosphate at its 5' end.[3]
