F-14258

F-14258 is a serotonin 5-HT_1B and 5-HT_1D receptor antagonist which was under development for the treatment of major depressive disorder (MDD) and obsessive–compulsive disorder (OCD) but was never marketed.^[1][2] It is taken orally.^[1] The drug was under development by Pierre Fabre.^[1][2] It reached the preclinical research stage of development prior to its discontinuation around 2002.^[1][2]

Other namesF14258

Routes of
administrationOral^[1]

Drug classSerotonin 5-HT_1B receptor antagonist; Serotonin 5-HT_1D receptor antagonist

ATC code

• None

Quick facts Clinical data, Other names ...

F-14258

Clinical data
Other names	F14258
Routes of administration	Oral[1]
Drug class	Serotonin 5-HT1B receptor antagonist; Serotonin 5-HT1D receptor antagonist
ATC code	None
Identifiers
CAS Number	194942-63-7
PubChem CID	9845946
ChemSpider	8021660
Chemical and physical data
Formula	C25H35N5O2
Molar mass	437.588 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(NC1=CC=C(OC)C(=C1)N2CCN(C)CC2)N3CCN(CCC=4C=CC=CC4)CC3
InChI InChI=1S/C25H35N5O2/c1-27-12-16-29(17-13-27)23-20-22(8-9-24(23)32-2)26-25(31)30-18-14-28(15-19-30)11-10-21-6-4-3-5-7-21/h3-9,20H,10-19H2,1-2H3,(H,26,31) Key:SDXUUOUVEULXIO-UHFFFAOYSA-N

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