FCGR1A

Mammalian protein found in Homo sapiens From Wikipedia, the free encyclopedia

High affinity immunoglobulin gamma Fc receptor I is a protein that in humans is encoded by the FCGR1A gene.[5][6][7]

PDBOrtholog search: PDBe RCSB
AliasesFCGR1A, CD64, CD64A, FCRI, IGFR1, Fc fragment of IgG receptor Ia
Quick facts Available structures, PDB ...
FCGR1A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesFCGR1A, CD64, CD64A, FCRI, IGFR1, Fc fragment of IgG receptor Ia
External IDsOMIM: 146760; MGI: 95498; HomoloGene: 475; GeneCards: FCGR1A; OMA:FCGR1A - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000566

NM_010186

RefSeq (protein)

NP_034316

Location (UCSC)Chr 1: 149.78 – 149.79 MbChr 3: 96.19 – 96.2 Mb
PubMed search[3][4]
Wikidata
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Interactions

The FcgRI binds the Fc portion of IgG and causes activation of the host cell via an intercellular ITAM motif.[8]

References

Further reading

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