FG-5893

FG-5893 is a chemical from the diphenylbutylpiperazine class of agents. It is a 5-HT1A agonist and a 5-HT2A antagonist.^[1]

Other namesFG5893

CAS Number

• 150527-23-4

PubChem CID

• 127728

IUPHAR/BPS

• 13

Quick facts Clinical data, Other names ...

FG-5893

Clinical data
Other names	FG5893
Identifiers
IUPAC name methyl 2-[4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl]pyridine-3-carboxylate
CAS Number	150527-23-4
PubChem CID	127728
IUPHAR/BPS	13
ChemSpider	113304
UNII	2QR7EI62WQ
CompTox Dashboard (EPA)	DTXSID50164565
Chemical and physical data
Formula	C27H29F2N3O3
Molar mass	481.544 g·mol−1
3D model (JSmol)	Interactive image
SMILES COC(=O)C1=C(N=CC=C1)N2CCN(CC2)CCCC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F
InChI InChI=1S/C27H29F2N3O2/c1-34-27(33)25-4-2-14-30-26(25)32-18-16-31(17-19-32)15-3-5-24(20-6-10-22(28)11-7-20)21-8-12-23(29)13-9-21/h2,4,6-14,24H,3,5,15-19H2,1H3 Key:NDCPNKXUTJGQQC-UHFFFAOYSA-N

Close

It is believed to be an anxiolytic agent with potential uses in the treatment of substance abuse disorders particularly alcoholism.^[2][3][4]

There is evidence for FG-5893 behaving as a SNDRI:^[5]

CNS review:^[6]